Magic mushroom improves mood and controls anxiety in cancer patients
Mushroom is one of the most common pizza topping and in some cultures it is referred as the umbrella for frog. Apart from adding taste to your pizza, pasta, mushroom contains a drug called as psilocybin, which can help anxiety and up lift mood of cancer patients. Psilocybin is a psychoactive or active ingredient found in varying concentrations in over 200 species of Basidiomycota mushrooms. These mushrooms are often called “magic mushrooms,” “zoomers”or “shrooms. The study reveals that advance stage cancer patients who generally experience anxiety can benefit from it without side effects.
About the study
The study was led by Charles S. Grob, M.D., of Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance. Dr. Grob conducted the study on 12 adults with advanced stage cancer and anxiety. The main objective of the study was to evaluate the safety and efficacy of psilocybin – a hallucinogen with some psychological effects similar to lysergic acid diethylamide (LSD).
The study included
Treatment in two six-hour sessions several weeks apart
One group of patient was given capsules of active psilocybin in a dose of 0.2 mg per kg body weight in one session and another group was given placebo in random order
Physiological responses like blood pressure, heart rate and temperature, and psychological responses including depression, mood and anxiety were measured or assessed
Frequency of analysis was before and at the end of the session, one day and two weeks after the session and at monthly intervals for the following six months.
The study scheduled to appear in the January 2011 print issue of Archives of General Psychiatry
Results of study
The study found that
anxiety scores improved at one and three months after treatment
mood was improved two weeks after treatment and a significant improvement in mood was observed at six months.
moderate doses of psilocybin given to patients with advanced-stage cancer and anxiety helps to reduce anxiety and improve mood.
Cancer Radiation Treatments: What Michael Douglas Can Expect
In last week’s segment I wrote about the need to “smell the roses” and to have some distractions and fun before and while you are undergoing cancer treatments. Today let’s get into some of the nitty-gritty of the various procedures, especially radiation treatment. Treating cancers is much like a horror show, so be prepared, it could get a bit rough and spooky here.
Just a few days ago I learned that the actor Michael Douglas was diagnosed with throat cancer and has just started his radiation and chemotherapy. His cancer is stage 4, which means his has spread somewhat from its origin; mine was stage 2 and did not spread. – One always feels a kind of kinship when another person is suffering from a cancer so similar to ones own. – Michael will go through the same procedures as I did in 2007. It will be very rough and bumpy for him. My heart really goes out to him and his family.
After my initial throat (and thyroid) surgery everything needed to have healed up nicely before my radiation therapy could begin. But there was one item that, though another patient pointed it out to me, the radiology doctors neglected to mention entirely; – it was the need to have one’s teeth and gums thoroughly examined before you start neck treatment. So off I went to see my dentist, and since I knew that I had one tooth that was on the “iffy” list, we decided to have it extracted rather than to invite trouble. Other patients I talked to had a number of their teeth pulled before undergoing this treatment. I lucked out again with only a single loss. You see, radiation makes a real mess of bad or in flamed tooth or gum tissue.
I already mentioned that receiving radiation treatment means you are town-bound for a good lengthy time. For my neck treatment I showed up every single work day for seven weeks straight. Naturally after a while I got to know my radiation technicians and the other staff at the cancer center pretty well. I talked to them, I joked with them, and almost became buddies with them.
Scott was one of the wonderful radiology techs. Like the engineer in the Star Trek series, Scotty had to sometime nudge and coerce the big radiation machinery back into life and working order. Personally I found all this technical medical stuff very fascinating, and he willingly explained to me how it all worked.
Just to reiterate (but, of course, you knew all this already), radiation treatment works by bombarding the areas of your tumor (plus surrounding areas where the cancers may have spread to, plus possible lymph node areas that might be cancerous) with a strong powerful x-ray type beam (in my case it was ionized photons). Cells really don’t like that at all. All cell structures get damaged by the effects of the radiation. Now the trick is, that healthy cells can recover much faster from the beam’s damage than cancer cells. You see, – them cancer things, they’re a bit dim and slow, and by the time the healthy cells have repaired their DNA and are more or less OK again, the sluggish cancer cells are blasted again with the next dose; and eventually they cannot keep up anymore, throw up their arms in disgust, and then they shrivel and die. This is, of course, exactly what is intended here. Hurray, let’s beam ‘em away, Scotty! – That is also the reason radiation session are scheduled so close to each other and over a lengthy period of time. (Well, to be honest, I actually did not fully understand that this was the way it all worked. See, one never stops learning.)
At the very first visit to the radiation therapy center, the doctors usual do a comprehensive survey on you. That means they determine (by using a scanner) where exactly your cancer is located (to minimize, as much as possible, radiating any healthy tissue). – And I already mentioned the little tattoos they put onto your body in order to aim the equipment (and its guide laser beams) precisely at your tumor and treatment areas.
Remedies for Cancer and Tumors
With my neck cancer I had to have my head immobilized, so I received a custom made mask which was then bolted to the treatment table. No way could I move my head at all. Yes, it was a little claustrophobic, I must admit. – Here is a picture of me on the table wearing this face mask. I heard of people that could not stand this procedure at all, and had to be heavily sedated in order to make it through their radiation sessions.
There was music offered during the treatment sessions, but it was not to my taste, so I brought my own CDs from home to be played while I was screwed. Screwed, via the face mask, to the treatment table that is. Of course you are all alone in the radiation chamber and the massive lead-lined doors are closed while you receive your dose. The staff is monitoring you from the outside through a video link.
The treatment table was elevated to the exact position for the machine to start giving me the beam bursts. The entire head (the business end where the beam comes out), was movable and could circle all around me. It looked very surreal and scientific. Here is another picture of me on the table. – Some times the table was cranked up way high so that I was more than five feet above the floor (high enough to requested an oxygen mask and a parachute for safety’s sake).
The actual radiation does not take very long at all. From a few seconds to up to a minute or so per target area, but I had nearly a dozen different areas that needed to be treated, so the entire process (most of it involving the positioning of me in the precise spot) lasted about 40 minutes. – You hear a curious buzzing and clicking sound when the radiation is actually being applied.
First I didn’t notice much change to my skin, neither to the outside of my neck, nor inside to my throat. I was told not to wear deodorant to the radiation sessions (they often have metals [mostly aluminum] in them which would interfere with the radiation), and I was told to apply a special radiation ointment (to minimize the skin burning damage) to the affected areas after each session. Also the liberal use of aloe-vera gel was recommended. – So it took quite some time until I became aware of any reddening and tanning of my skin.
But about 4 weeks into the 7 week process, I began to really feel the effects. My throat started to ached mildly at first, and as the treatments went on further, the hurting became more severe and pain medication became a must. (I hate it when doctors talk about “discomfort” when it hurts like hell).
At about that time my normal (oral) meals started to become really difficult. Solid food was minimized, then stopped, and soup time arrived. Luckily my dear wife is an excellent cook, and we had some rather memorable soupy culinary delights. – And a little further into the treatment it was time to switch to the feeding tube. That on the other hand was no delight what-so-ever. Most disagreeable and horrid ! Cans of fortified nutritional stuff being pushed by a giant syringe through a tube directly into your stomach. It was mostly vanilla or choco flavors, and I soon hated them intensely. The mere odor of it made me run for cover (remember my ability to smell remained operational throughout this ordeal). – Luckily the feeding tube time lasted for only a little over 3 weeks and slowly I was able to have some real food down my throat again. What a relief!! – Believe me, that period on the PEG-tube was not at all to my liking.
And, as predicted, during that period, my taste buds went bye-bye. Not all at once, but gradually. I noticed that more and more things started to taste like really bland card board. Yuck! – And towards the end of my radiation treatments it was impossible for me to taste anything at all.
It took a good year until all my taste buds came back home. They came back as gradually as they left me. For instance, suddenly I noticed I could taste coffee again (but not yet tea). It was a little like the TV commercials with “Mikey likes it” – I had to use the trial and error method to see what “my personal” new flavor of the day was.
On a more somber note, a former neighbor of mine had a similar throat cancer, but not all of his taste buds regenerated successfully. To this day (eight years since treatment) he still cannot taste anything sweet. – Again, I found myself really lucky – and I am extremely grateful for that.
I was warned that after the radiation treatments were over, I would by no means feel better right away, on the contrary, the deterioration of the insides of my throat would continue for a few additional weeks before healing and improvements would start. And sure enough, I felt really dreadful for another two weeks. Slept or “zombied” through life for most of that time (well, the pain medication amplified this in that they made me very drowsy too). – So, please don’t schedule any trips or important things right after the end of your radiation treatment for throat cancer.
At one point I asked one of the radiation technicians which cancer they thought was the most difficult to treat, and the answer was (interestingly) anal cancer, but closely followed by throat cancer. Throat cancer because of all the possible side effects to various important areas in the neck, like teeth and gums, thyroid gland, vocal chords, tongue, taste buds, etc. – But I never found out why anal cancers are so difficult to treat with radiation.
At the end of my first 7 week treatment I was leaving good friends behind at the cancer center (I didn’t know then that I’d be back for an encore performance). – So, what do you say to a radiology technician at the end of your treatment? – I hope I never see you again? Good riddance? – I settled for the following: thank you so very much for all you did for me, and I hope we’ll meet again at the movies or at the supermarket in town, but please – not here again! (I also purchased two large boxes of chocolates which I left at the treatment center. One for the front office staff, one for the technicians and nurses).
Well, I did get another 5 weeks of radiation onto my arm and lymph nodes a few months later. And yes, I purchased more chocolate boxes!
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My chemo for the throat cancer happened concurrently with my radiation treatments, which meant that on Mondays I had them both. Radiation in the morning and chemo in the afternoon. More about the chemotherapy part of my treatment in next week’s installment which I entitled “Witches Brew”. Stay tuned for that potent concoction.
Here is to your health!
HD in Oregon
Osteoporosis Drugs May Boost Throat Cancer Risk
A new study suggests that people who take bone-strengthening drugs for osteoporosis for several years may have a slightly higher risk of developing esophageal cancer.
British researchers tracked almost 3,000 people with cancer of the esophagus or throat for eight years and compared each one to five similar people who didn’t have the disease matched for age and sex. The study revealed that 90 of the cancer patients and 345 people in the comparison group had been prescribed bone-building pills called bisphosphonates.
The findings are in contrast to a separate study published in the Journal of the American Medical Association early last month. That research used the same data of patients and concluded that there was no significant increase in esophageal cancer risk in users of the osteoporosis drugs. Authors of the new research suggest that more study is needed to verify if oral bisphosphonate intake really does increase esophageal cancer risk.
“But the risk, if it does exist, is small in absolute terms and is not something people taking these drugs should worry too much about,” said epidemiologist Jane Green, PhD, of Oxford University.
Oral bisphosphonates, sold as Fosamax, Actonel, Boniva and other brands, are a type of drug used after menopause to treat osteoporosis and other bone diseases and are the most commonly recommended treatment for such conditions.
Experts say it is still unclear why the drugs might lead to throat cancer. They do know however, that bisphosphonates can cause inflammation in the esophagus, which could cause cancer to develop more easily.
The research, published in the British Medical Journal on Friday, was only observational and is not the kind of evidence that can show whether such drugs cause cancer.